Acute renal failure following Entamoeba histolytica treatment in a 9-year-old girl

Abstract

A 9-year-old girl entered to the emergency department with fever, dysentery, neurological signs, and renal failure following an epidemic of amebiasis. She had used 5 days metronidazole (30 mg/kg/daily) before she was affected to hemolytic uremic syndrome (HUS) and seizure, blindness, and ataxia. We hold using of metronidazole and by supportive therapy all symptoms alleviated and she left hospital in 8 th day, after 1-month she was healthy without need to use any drug. amebiasis may cause to HUS by different mechanisms, but metronidazole as a causing and defining of symptoms in HUS should be considered.