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dc.contributor.authorAdibkia, K
dc.contributor.authorBarzegar-Jalali, M
dc.contributor.authorJavadzadeh, Y
dc.contributor.authorMaheri-Esfanjani, H
dc.date.accessioned2018-08-26T08:32:52Z
dc.date.available2018-08-26T08:32:52Z
dc.date.issued2012
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/52351
dc.description.abstractObjectives: Spray drying is the most widely used techniqueintended for drying of pharmaceutical products as well as manufacturing of powder with desired characteristics.It is a continuous operation in which almost any pumpable liquid can be converted into a free flowing powder. Considering uniformity of formed particles and well-control on particle size, spray drying is efficiently applicable in the drug delivery systems. This method has found to be a potential way for systematic delivery of therapeutic peptides, proteins and also antibiotics. Methods: In this study, the procedures and aplications of spray drying were reviewed and the effect of diffirent affecting parameters was explained. Results: Spray drying is extensively used to dry heat sensitive products like enzymes and proteins with minimum loss on activity and produce drugs with improved solubility as well as drying of nanoparticles, microencapsulation, granulation and coating beyond its well-known background on drying of liquids. Conclusion: Spray drying could be of beneficial in formulation of drug delivery systems with desired physicochemical characteristics.
dc.language.isoPersian
dc.relation.ispartofPharmaceutical Sciences
dc.subjectdrug
dc.subjectarticle
dc.subjectdrug coating
dc.subjectdrug delivery system
dc.subjectdrug formulation
dc.subjectdrug solubility
dc.subjectgranulation tissue
dc.subjectliquid
dc.subjectmicroencapsulation
dc.subjectparticle size
dc.subjectpowder
dc.subjectspray drying
dc.titleA review on the methods and applications of spray drying technology
dc.typeArticle
dc.citation.volume18
dc.citation.issue2
dc.citation.spage119
dc.citation.epage132
dc.citation.indexScopus


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