| dc.contributor.author | Jouyban-Gharamaleki, A | |
| dc.contributor.author | Barzegar-Jalali, M | |
| dc.contributor.author | Acree, WE | |
| dc.date.accessioned | 2018-08-26T08:31:37Z | |
| dc.date.available | 2018-08-26T08:31:37Z | |
| dc.date.issued | 1998 | |
| dc.identifier.uri | http://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/52178 | |
| dc.description.abstract | Applicability of the well-established cosolvency equation, i.e. combined nearly ideal binary solvent/Redlich-Kister, CNIBS/R-K, model for calculating the solubility of structurally related drugs in a given cosolvent and water mixtures is presented. The accuracy and predictability of the model are also compared with those of two other models. Computational results show that the CNIBS/R-K model provides very reasonable solubility predictions for the solutes considered, and the CNIBS/R-K model is superior to the other two models. (C) 1998 Elsevier Science B.V. All rights reserved. | |
| dc.language.iso | English | |
| dc.relation.ispartof | INTERNATIONAL JOURNAL OF PHARMACEUTICS | |
| dc.subject | cosolvency | |
| dc.subject | structurally related drugs | |
| dc.subject | solubility | |
| dc.subject | combined nearly ideal binary solvent Redlich-Kister equation | |
| dc.title | Solubility correlation of structurally related drugs in binary solvent mixtures | |
| dc.type | Article | |
| dc.citation.volume | 166 | |
| dc.citation.issue | 2 | |
| dc.citation.spage | 205 | |
| dc.citation.epage | 209 | |
| dc.citation.index | Web of science | |
| dc.identifier.DOI | https://doi.org/10.1016/S0378-5173(98)00044-1 | |
