Coumarins from the roots of Prangos uloptera

Abstract

Three new coumarins, 6-O-[beta-D-apiofuranosyl-(1 -> 6)-beta-D-glucopyranosyl]-prenyletin, 3"-O-[beta-D-apiofuranosyl-(1 -> 6)-beta-D-glucopyranosyl]-oxypeucedanin hydrate and 2"-O-[beta-D-apiofuranosyl-(1 -> 6)-beta-D-glucopyranosyl]-oxypeucedanin hydrate, together with six known coumarins, 3''-O-[beta-D-apiofuranosyl-(1 -> 6)-beta-D-glucopyranosyl]-heraclenol, 3''-O-(beta-D-glucopyranosyl)-heraclenol, tortuoside, 3"-O-(beta-D-glucopyranosyl)-oxypeucedanin hydrate, heraclenol and oxypeucedanin hydrate, have been isolated from the roots of Prangos uloptera, and the structures of these coumarins were unequivocally determined by spectroscopic means, notably UV, HRESIMS, and 1D and 2D NMR spectroscopy. (C) 2008 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.