The effect of Kombucha on post-operative intra-abdominal adhesion formation in rats

Abstract

Background Peritoneal adhesions are fibrous bands of tissues formed between organs that are normally separated and/or between organs and the internal body wall after peritoneal injury. The aim of the study was to investigate the effect of intra-peritoneal administration of Kombucha on intra-peritoneal adhesions. Materials and methods Eighty Wistar rats were subjected to standardized lesion by scraping model and were randomly divided into two groups. Group I received no treatment, and Group II received 15 ml of Kombucha solution intra-peritoneally. On the post-operative 14th day adhesion intensity score, inflammatory cell reaction and number of adhesion bands were determined. Results In the control group, there were no rats with grade 0 and I adhesions. In the group II, there were 26 rats ( 78.8%) with grade 0-2 adhesions. Adhesion intensity was significantly less in group II (P<0.0001). Number of adhesion bands was significantly less in group II (P<0.001). Conclusion it was concluded that intra-peritoneal administration of Kombucha might be useful for preventing peritoneal adhesions.