Biological activity of quercetin-3-O-glucoside, a known plant flavonoid

Abstract

Cytotoxic, phytotoxic, antimicrobial and antioxidant effects of quercetin 3-O-glucoside (Q3G) isolated by HPLC from aerial parts of Prangos ferulaceae was studied by MTT assay, lettuce germination assay, disk diffusion and DPPH method. Our results showed that Q3G exhibits high antioxidant effect with RC50 of 22 mu g/mL, it has low cytotoxicity and no antibacterial effects. Q3G exhibits high phytotoxic effect with IC50 value of 282.7 mu g/ml, as well. It is assumed that Q3G does not play a defense role in plants and it may act as an allelopatic agent.