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dc.contributor.authorMortazavi, F
dc.contributor.authorSakha, SH
dc.contributor.authorNejati, N
dc.date.accessioned2018-08-26T08:14:49Z
dc.date.available2018-08-26T08:14:49Z
dc.date.issued2009
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/50980
dc.description.abstractIntroduction. Acute kidney failure (AKF) is a common clinical problem in neonatal intensive care units and is usually associated with a contributing condition such as sepsis, asphyxia, and heart failure. The aim of this study was to determine the types, frequency of associated contributing conditions, and short-term outcome of neonatal AKF. Materials and Methods. Medical records of neonates with a diagnosis of AKF from March 2003 to September 2006 were studied in a tertiary care children's hospital in Tabriz, Iran. Results. Of 6042 hospitalized neonates, 151 with documented AKF (100 boys and 51 girls) were reviewed in the study. Ninety-one patients (60.3%) had been referred from other cities. Fifty-seven patients (37.7%) developed AKF following a surgery. Causes of AKF were intrinsic kidney failure in 52.3%, prerenal in 42.4%, and postrenal in 5.3%. Oliguria was observed in 72.2% of the patients. Perinatal asphyxia was present in 29.8% of the neonates, sepsis in 28.5%, respiratory distress syndrome in 25.2%, dehydration in 24.2%, and heart failure in 21.2%. Most patients (85.4%) had more than 1 associated contributing condition. Mortality rate was 20.5%. Most patients (76.2%) were discharged with normal kidney function and 3.3% with diminished kidney function. Initial admission to NICU, female sex, septicemia, and the need for mechanical ventilation were associated with a higher mortality rate. Conclusions. The frequency of associated contributing conditions and short-term outcome of neonatal AKF in our institution is comparable with other studies; however, intrinsic kidney failure comprises the most common form of AKF in our patients.
dc.language.isoEnglish
dc.relation.ispartofIRANIAN JOURNAL OF KIDNEY DISEASES
dc.subjectacute kidney failure
dc.subjectnewborn infants
dc.subjectasphyxia
dc.subjectsepsis
dc.titleAcute Kidney Failure in Neonatal Period
dc.typeArticle
dc.citation.volume3
dc.citation.issue3
dc.citation.spage136
dc.citation.epage140
dc.citation.indexWeb of science
dc.citation.URLhttp://www.ijkd.org/index.php/ijkd/article/view/175


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