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dc.contributor.authorArdalan, M
dc.contributor.authorShoja, MM
dc.date.accessioned2018-08-26T08:14:26Z
dc.date.available2018-08-26T08:14:26Z
dc.date.issued2009
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/50950
dc.description.abstractCytomegalovirus (CMV) is an important pathogen in organ-transplant recipients. There have been frequent reports of CMV-induced adrenal insufficiency in patients with human immunodeficiency virus infection. Herein, we report CMV-induced renal insufficiency in a renal transplant recipient. A 24-year-old woman had gradual onset of weakness, anorexia, nausea, hypotension, and skin hyperpigmentation at 5 months after renal transplantation. The immunosuppression regimen included cyclosporine, mycophenolate mofetil, and corticosteroid (prednisolone, 5 mg/d). Recent history included acute CMV infection, which was treated with ganciclovir. Basal serum cortisol concentration was 4 mu g/dL, and stimulated serum cortisol concentration was less than 10 mu g/dL. All clinical signs and symptoms and hypotension gradually improved after the oral prednisolone dose was increased to 10 mg/d. Clinicians must be aware of the possibility of CMV-induced adrenal insufficiency in renal transplant recipients. The condition may be symptomatic despite low-dose prednisolone therapy.
dc.language.isoEnglish
dc.relation.ispartofTRANSPLANTATION PROCEEDINGS
dc.relation.ispartof11th Congress of the Middle-East-Society-for-Organ-Transplantation
dc.titleCytomegalovirus-induced Adrenal Insufficiency in a Renal Transplant Recipient
dc.typeArticle; Proceedings Paper
dc.citation.volume41
dc.citation.issue7
dc.citation.spage2915
dc.citation.epage2916
dc.citation.indexWeb of science
dc.identifier.DOIhttps://doi.org/10.1016/j.transproceed.2009.07.024


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