dc.contributor.author | Ardalan, M | |
dc.contributor.author | Shoja, MM | |
dc.date.accessioned | 2018-08-26T08:14:26Z | |
dc.date.available | 2018-08-26T08:14:26Z | |
dc.date.issued | 2009 | |
dc.identifier.uri | http://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/50950 | |
dc.description.abstract | Cytomegalovirus (CMV) is an important pathogen in organ-transplant recipients. There have been frequent reports of CMV-induced adrenal insufficiency in patients with human immunodeficiency virus infection. Herein, we report CMV-induced renal insufficiency in a renal transplant recipient. A 24-year-old woman had gradual onset of weakness, anorexia, nausea, hypotension, and skin hyperpigmentation at 5 months after renal transplantation. The immunosuppression regimen included cyclosporine, mycophenolate mofetil, and corticosteroid (prednisolone, 5 mg/d). Recent history included acute CMV infection, which was treated with ganciclovir. Basal serum cortisol concentration was 4 mu g/dL, and stimulated serum cortisol concentration was less than 10 mu g/dL. All clinical signs and symptoms and hypotension gradually improved after the oral prednisolone dose was increased to 10 mg/d. Clinicians must be aware of the possibility of CMV-induced adrenal insufficiency in renal transplant recipients. The condition may be symptomatic despite low-dose prednisolone therapy. | |
dc.language.iso | English | |
dc.relation.ispartof | TRANSPLANTATION PROCEEDINGS | |
dc.relation.ispartof | 11th Congress of the Middle-East-Society-for-Organ-Transplantation | |
dc.title | Cytomegalovirus-induced Adrenal Insufficiency in a Renal Transplant Recipient | |
dc.type | Article; Proceedings Paper | |
dc.citation.volume | 41 | |
dc.citation.issue | 7 | |
dc.citation.spage | 2915 | |
dc.citation.epage | 2916 | |
dc.citation.index | Web of science | |
dc.identifier.DOI | https://doi.org/10.1016/j.transproceed.2009.07.024 | |