Comparative assessment of Helicobacter pylori colonization in children tonsillar tissues

Abstract

Objective: The objective was to survey the results of RUT (rapid urease test) in children tonsillar tissues. Methods: In a prospective clinical study 285 children (4-14 years) tonsillar tissue tested with RUT (rapid urease test) and histopathologic biopsy and simultaneously serum IgG Helicobacter pylori level was measured for all patients. Results: One hundred and thirteen patients (39.6%) were positive to H. pylori in histopathologic examination. Forty patients (14%) had positive RUT and 15 patients had positive serum IgG anti-H. pylon level. In 40 patients the results in both histopathology and RUT were positive (P = 0.000) although in 172 patients the results in both histopatologhic and RUT were negative (P = 0.000). Conclusions: This study showed that H. pylori was present in tonsillar tissue and RUT is not sensitive enough for diagnosis of H. pylori in tonsillar tissue. Indicating that H. pylori has a possible role in reservoir of H. pylon in children. (c) 2009 Elsevier Ireland Ltd. All rights reserved.