CHEMICAL COMPOSITION, FREE-RADICAL-SCAVENGING AND INSECTICIDAL ACTIVITIES OF THE AERIAL PARTS OF STACHYS BYZANTINA

Abstract

Stachys byzantina K. Koch. is an Iranian endemic species of the genus Stachys L., which comprises about 300 species, and is one of the largest genera of the family Lamiaceae. A combination of solid phase extraction (SPE) and high pressure liquid chromatography (HPLC) of the methanolic extract of the aerial parts of S. byzantina afforded three phenylethanoids, 2'-O-arabinosyl verbascoside (1), verbascoside (2), aeschynanthoside C (3) and three flavones apigenin 7-O-glucoside (4), apigenin 7-O-(6-p-coumaroyl)-glucoside (5) and apigenin (6). The structures of these compounds were determined by spectroscopic methods. Free-radical-scavenging and insecticidal properties of the crude extracts, the fractions and the isolated compounds were assessed.