| dc.contributor.author | Ataie, Z | |
| dc.contributor.author | Golzar, MG | |
| dc.contributor.author | Babri, S | |
| dc.contributor.author | Ebrahimi, H | |
| dc.contributor.author | Mohaddes, G | |
| dc.date.accessioned | 2018-08-26T08:08:15Z | |
| dc.date.available | 2018-08-26T08:08:15Z | |
| dc.date.issued | 2011 | |
| dc.identifier.uri | http://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/50305 | |
| dc.description.abstract | Aim: Epilepsy is one of the most common neurologic problems worldwide. A relationship between epilepsy and hormones has been demonstrated. This study was designed to investigate the effect of seizure on blood ghrelin level. Methods: Twenty male Wistar rats were divided into two groups. The control group received saline and the pentylenetetrazole (PTZ) group received a single convulsive dose (50 mg/kg) of PTZ. Thirty minutes later blood samples were collected and acylated and unacylated ghrelin levels in the plasma were assayed. Results: Acylated or active form of ghrelin decreased significantly (p < 0.05) after a PTZ-induced seizure, but the reduction of unacylated and total blood ghrelin levels failed to reach statistical significance. Conclusion: These findings may reflect that PTZ-induced epilepsy decreases AG of plasma. (C) 2011 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved. | |
| dc.language.iso | English | |
| dc.relation.ispartof | SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | |
| dc.subject | Seizure | |
| dc.subject | Ghrelin | |
| dc.subject | PTZ | |
| dc.title | Does ghrelin level change after epileptic seizure in rats? | |
| dc.type | Article | |
| dc.citation.volume | 20 | |
| dc.citation.issue | 4 | |
| dc.citation.spage | 347 | |
| dc.citation.epage | 349 | |
| dc.citation.index | Web of science | |
| dc.identifier.DOI | https://doi.org/10.1016/j.seizure.2011.01.001 | |
