Anethum graveolens L. supplementation has anti-inflammatory effect in type 2 diabetic patients

Abstract

This randomized, double-blind, placebo-controlled clinical trial designed to assess the effects of Anethum graveolens L. supplementation on the pro-inflammatory biomarkers (IL-6, TNF-alpha) and acute phase protein hs-CRP concentrations in type 2 diabetic patients. For 8 weeks, intervention group received 3.3 gm/day Anethum powder and placebo group received same amounts starch. At the onset and at the end of study collected 5 cc blood samples. The concentration of hs-CRP was measured by spectrophotometer method. IL-6 and TNF-alpha were assayed using ELISA method. Serum concentration of IL-6, TNF-alpha and hs-CRP decreased significantly at the end of study in intervention group (p<0.031, p<0.026, and p<0.045 respectively). Further clinical studies are needed to confirm the results.