| dc.contributor.author | Hashemzadeh, N | |
| dc.contributor.author | Jouyban, A | |
| dc.date.accessioned | 2018-08-26T07:45:09Z | |
| dc.date.available | 2018-08-26T07:45:09Z | |
| dc.date.issued | 2015 | |
| dc.identifier.uri | http://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/48313 | |
| dc.description.abstract | Ketoconazole is an important drug with low water solubility. Its low aqueous solubility could be increased using various methods such as by the addition of a pharmaceutical cosolvent. The solubility of ketoconazole in ethanol + water mixtures at 293.2, 298.2, 303.2, and 308.2K were determined, and the results showed that the addition of ethanol increased the solubility and the maximum value was obtained at 80% of ethanol. The generated data were mathematically represented using the Jouyban-Acree model within an acceptable accuracy. | |
| dc.language.iso | English | |
| dc.relation.ispartof | CHEMICAL ENGINEERING COMMUNICATIONS | |
| dc.subject | Ethanol plus water mixtures | |
| dc.subject | Jouyban-Acree model | |
| dc.subject | Ketoconazole | |
| dc.subject | Solubility prediction | |
| dc.title | Solubility of Ketoconazole in Ethanol plus Water Mixtures at Various Temperatures | |
| dc.type | Article | |
| dc.citation.volume | 202 | |
| dc.citation.issue | 9 | |
| dc.citation.spage | 1211 | |
| dc.citation.epage | 1215 | |
| dc.citation.index | Web of science | |
| dc.identifier.DOI | https://doi.org/10.1080/00986445.2014.912636 | |
