| dc.description.abstract | Introduction One of diagnostic criteria for Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS) is Pao(2)/Fio(2) (PF) ratio <= 300 for ALI or <= 200 for ARDS. This criteria requires invasive arterial sampling. Measurement of Spo(2)/Fio(2) (SF) ratio by pulse oximetry test may be a reliable non invasive alternative to the PF ratio. Materials and Methods In a cross sectional study we enrolled 105 sample of patients with ALI or ARDS, to determine the Spo(2)/Fio(2) (SF). Pao(2) was measured through arterial blood sampling and Spo(2) measured with pulse oximetry and documented within 5 minutes of each other. Results The relationship between SF and PF ratio was described by the following equation: SF=57+0/61PF (P<0/001). Spo(2)/Fio(2) (SF) ratios of 181 and 235 can be substituted pao(2)/fio(2) (PF) ratio of 200 and 300 in ARDS and ALI respectively. The ALI, SF cutoff of 235 had 57% sensitivity and 100% specificity, and ARDS, SF cutoff of 181 had 71% sensitivity and 82% specificity. Conclusion Spo(2)/Fio(2) (SF) ratio is a reliable noninvasive marker to determine children with ALI or ARDS and can be used instead of it. | |
