| dc.description.abstract | To compare vascular Doppler waveform indices, particularly in the common carotid arteries, between cirrhotic and healthy subjects. A total of 60 patients with Class-B cirrhosis and 60 healthy matched counterparts were enrolled in this prospective study. Vascular Doppler waveform parameters including resistance and/or pulsatility indices (RI and PI, respectively) were obtained from the common carotid, renal, celiac, superior mesenteric, femoral and brachial arteries. Compared to patients, healthy subjects had significantly higher mean PI and RI obtained from the common carotid (1.53 +/- A 0.20 vs. 1.43 +/- A 0.14, p = 0.03; 0.75 +/- A 0.02 vs. 0.72 +/- A 0.02, p < 0.001, respectively) and celiac arteries (2.00 +/- A 0.36 vs. 1.81 +/- A 0.34, p = 0.03; 0.80 +/- A 0.03 vs. 0.78 +/- A 0.02, p < 0.001, respectively). Both the mean PI and RI derived from the renal arteries, in contrast, were significantly higher in patients compared to that in controls (1.05 +/- A 0.13 vs. 1.11 +/- A 0.07, p = 0.03; 0.59 +/- A 0.03 vs. 0.63 +/- A 0.03, p < 0.001, respectively). The mean vascular impedance values obtained from the remaining arteries were comparable between the two groups. Blood flow increases in the common carotid and celiac arteries of Class-B cirrhotic patients with elevated renovascular impedance. | |
