Early stage screening of breast cancer using electrochemical biomarker detection

Abstract

Recently researchers have driven their attention in the development of biosensors for breast cancer detection using different biomarkers. This review reports a systematic study of the usefulness of marker based electrochemical biosensors in breast cancer and its early diagnosis. Also, various types of electroanalytical methods for early stage screening of breast cancer were discussed. The emphasis is placed on immune-, geno- cyto- and enzyme-biosensing strategies. In addition, the advantages offered by some nano-materials in detection of breast cancer biomarkers are illustrated with representative recent examples that highlight the scientific interest in widening the use of new materials/methods in electrochemical biosensing methods. We also present a comprehensive overview of current developments and key issues in the determination of some breast cancer biomarkers, with an emphasis on evaluating the methods. (C) 2017 Elsevier B.V. All rights reserved.