Angiogenic potential of YKL-40 in the dynamics of tumor niche

dc.contributor.author	Pouyafar, A
dc.contributor.author	Heydarabad, MZ
dc.contributor.author	Mahboob, S
dc.contributor.author	Mokhtarzadeh, A
dc.contributor.author	Rahbarghazi, R
dc.date.accessioned	2018-08-26T07:11:51Z
dc.date.available	2018-08-26T07:11:51Z
dc.date.issued	2018
dc.identifier.uri	http://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/44494
dc.description.abstract	A multitude of clinical studies showed the elevation of YKL-40 in subjects with different kinds of tumors. It is predicted that an inherent correlation exists between survivals of cancer patients with total YKL-40 serum levels, making this factor as a potential novel biomarker. However, the crucial role of YKL-40 in the dynamics of cancers, especially angiogenesis, has not yet been completely addressed. In this review, we highlighted the various facets of YKL-40 and its importance in cancer biology as a bio-shuttle in gene therapy.
dc.language.iso	English
dc.relation.ispartof	BIOMEDICINE & PHARMACOTHERAPY
dc.subject	Cancer biology
dc.subject	Angiogenesis
dc.subject	YKL-40 factor
dc.title	Angiogenic potential of YKL-40 in the dynamics of tumor niche
dc.type	Article
dc.citation.volume	100
dc.citation.spage	478
dc.citation.epage	485
dc.citation.index	Web of science
dc.identifier.DOI	https://doi.org/10.1016/j.biopha.2018.02.050

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