Determining the expression rate of the IgM and IgA in B cell lymphomas by immunohistochemistry.

Abstract

This study aimed at assessing the expression rate of IgA and IgM in B cell lymphoma immunohistochemically. Paraffin-embedded specimens of NHL evaluated for presence of CD20 by immunohistochemical staining and then, the positive cases were again immunohistochemically assessed for expression of IgM and IgA. Fifty two paraffin-embedded specimens evaluated. Thirty six cases (69.2%) were positive for the CD20. The mean age of these patients (CD20+ cases) was 50.0 +/- 23.6 years. Twenty two cases (61%) were male and 14 cases (39%) were female. The frequency of the IgM+, IgA+ and IgA/IgM+ (simultaneous) cases was 15 (41.7%), 9 (25%) and 4 (11.1%), respectively. The current rates are in the range of similar reports in the literature.