Show simple item record

dc.contributor.authorGhaffari, A
dc.contributor.authorSomi, MH
dc.contributor.authorSafaiyan, A
dc.contributor.authorModaresi, J
dc.contributor.authorOstadrahimi, A
dc.date.accessioned2018-08-26T06:12:51Z
dc.date.available2018-08-26T06:12:51Z
dc.date.issued2012
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/42848
dc.description.abstractGastric cancer is the fourth most common malignancy in the world. Honey is a complex mixture of special biological active constituents. Honey possesses antioxidant and antitumor properties. Nutritional studies have indicated that consumption of honey modulates the risk of developing gastric cancer. On the other hand, apoptosis has been reported to play a decisive role in precancerous changes. Our chief study was conducted to assess the relationship between consumption of honey and apoptosis in human gastric mucosa.This cross-sectional study was conducted on 98 subjects over 18 years old, referred to two hospitals in Tabriz, Iran. Subjects were undergone an upper gastrointestinal endoscopy, 62 subjects were finally enrolled. Honey consumption was assessed by a Food Frequency Questionnaire (FFQ) and apoptosis was detected by TUNEL technique. We tested polynomial curve to find the best fit between honey consumption and apoptosis.A positive relation between honey consumption and apoptosis was found (P=0.024). Our results indicated that the final and the best fit curve was: apoptosis = 1.714+1.648(honey amount) - 0.533(honey amount)2 +1.833×10-5(honey amount)7.Honey consumption had positive effects on gastric cancer by inducing apoptosis in gastric mucosa.
dc.language.isoEnglish
dc.relation.ispartofHealth promotion perspectives
dc.titleHoney and apoptosis in human gastric mucosa.
dc.typearticle
dc.citation.volume2
dc.citation.issue1
dc.citation.spage53
dc.citation.epage9
dc.citation.indexPubmed
dc.identifier.DOIhttps://doi.org/10.5681/hpp.2012.007


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record