نمایش پرونده ساده آیتم

dc.contributor.authorAzizollahi, HR
dc.contributor.authorRafeey, M
dc.date.accessioned2018-08-26T05:37:38Z
dc.date.available2018-08-26T05:37:38Z
dc.date.issued2016
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/39908
dc.description.abstractGastroesophageal reflux disease (GERD) occurs in pediatric patients when reflux of gastric contents presents with troublesome symptoms. The present study compared the effects of omeprazole and ranitidine for the treatment of symptomatic GERD in infants of 2-12 months.This study was a clinical randomized double-blind trial and parallel-group comparison of omeprazole and ranitidine performed at Children Training Hospital in Tabriz, Iran. Patients received a standard treatment for 2 weeks. After 2 weeks, the patients with persistent symptoms were enrolled in this randomized study.We enrolled 76 patients in the present study and excluded 16 patients. Thirty patients each were included in group A (ranitidine) and in group B (omeprazole). GERD symptom score for groups A and B was 47.17آ±5.62 and 51.93آ±5.42, respectively, with a P value of 0.54, before the treatment and 2.47آ±0.58 and 2.43آ±1.15, respectively, after the treatment (P=0.98). No statistically significant differences were found between ranitidine and omeprazole in their efficacy for the treatment of GERD.The safety and efficacy of ranitidine and omeprazole have been demonstrated in infants. Both groups of infants showed a statistically significant decrease in the score of clinical variables after the treatment.
dc.language.isoEnglish
dc.relation.ispartofKorean journal of pediatrics
dc.titleEfficacy of proton pump inhibitors and H2 blocker in the treatment of symptomatic gastroesophageal reflux disease in infants.
dc.typearticle
dc.citation.volume59
dc.citation.issue5
dc.citation.spage226
dc.citation.epage30
dc.citation.indexPubmed
dc.identifier.DOIhttps://doi.org/10.3345/kjp.2016.59.5.226


فایلهای درون آیتم

فایلهاسایزفرمتنمایش

هیچ فایل مرتبطی وجود ندارد

این آیتم در مجموعه های زیر مشاهده می شود

نمایش پرونده ساده آیتم