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dc.contributor.authorReaghi, S
dc.contributor.authorHaghighi, A
dc.contributor.authorHarandi, MF
dc.contributor.authorSpotin, A
dc.contributor.authorArzamani, K
dc.contributor.authorRouhani, S
dc.date.accessioned2018-08-26T05:36:36Z
dc.date.available2018-08-26T05:36:36Z
dc.date.issued2016
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/39596
dc.description.abstractFascioliasis is one of the most zoonotic diseases with global extension. As the epidemiological distribution of Fasciola may lead to various genetic patterns of the parasite, the aim of this study is to identify Fasciola hepatica based on spermatogenesis, and phylogenetic analysis using mitochondrial (nicotiamide adenine dinucleotide dehydrogenase subunit I [ND1] and cytochrome oxidase subunit I) gene marker.In this study, 90 F. hepatica collected from 30 cattle at slaughterhouse located in three different geographical locations in the North-East of Iran were evaluated based on spermatogenetic ability and internal transcribed spacer 1 gene restriction fragment length polymorphism pattern. Genetic diversity and phylogenetic relationship using mtDNA gene marker for the isolates from the North-East of Iran, and other countries were then analyzed.Partial sequences of mtDNA showed eight haplotypes in both genes. The phylogenic analysis using neighbor joining as well as maximum likelihood methods showed similar topologies of trees. Pairwise fixation index between different F. hepatica populations calculated from the nucleotide data set of ND1 gene are statistically significant and show the genetic difference.F. hepatica found in this region of Iran has different genetic structures through the other Fasciola populations in the world.
dc.language.isoEnglish
dc.relation.ispartofVeterinary world
dc.titleMolecular characterization of Fasciola hepatica and phylogenetic analysis based on mitochondrial (nicotiamide adenine dinucleotide dehydrogenase subunit I and cytochrome oxidase subunit I) genes from the North-East of Iran.
dc.typearticle
dc.citation.volume9
dc.citation.issue9
dc.citation.spage1034
dc.citation.epage1038
dc.citation.indexPubmed
dc.identifier.DOIhttps://doi.org/10.14202/vetworld.2016.1034-1038


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