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dc.contributor.authorSalehiabar, M
dc.contributor.authorNosrati, H
dc.contributor.authorDavaran, S
dc.contributor.authorDanafar, H
dc.contributor.authorManjili, HK
dc.date.accessioned2018-08-26T04:56:15Z
dc.date.available2018-08-26T04:56:15Z
dc.date.issued2018
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/38468
dc.description.abstractNatural L-aspartic acid coated iron oxide magnetic nanoparticles (Asp@IONPs) were prepared by a one pot, in-situ and green co-precipitation method in an aqueous medium. Functionalized iron oxide magnetic nanoparticles (IONPs) were characterized by Vibrating Sample Magnetometer (VSM), X-ray diffraction (XRD), differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM) and Transmission electron microscopy (TEM) techniques. Cellular toxicity of IONPs was also investigated on HEK-293 cell lines. The results showed that the zeta potential of Asp@IONPs was about -21.1?mV and the average size was 17.80آ±3.09?nm. Cell toxicity results show that as prepared IONPs are biocompatible. Asp@IONPs show the possibility of using these nanoparticles in the development of in vitro and in vivo biomedical fields due to do not possess a toxic effect, good ?-potential and related small and narrow size distribution.
dc.language.isoEnglish
dc.relation.ispartofDrug research
dc.titleFacile Synthesis and Characterization of L-Aspartic Acid Coated Iron Oxide Magnetic Nanoparticles (IONPs) For Biomedical Applications.
dc.typearticle
dc.citation.volume68
dc.citation.issue5
dc.citation.spage280
dc.citation.epage285
dc.citation.indexPubmed
dc.identifier.DOIhttps://doi.org/10.1055/s-0043-120197


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