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dc.contributor.authorMohammadi, H
dc.contributor.authorSharafkandi, N
dc.contributor.authorHemmatzadeh, M
dc.contributor.authorAzizi, G
dc.contributor.authorKarimi, M
dc.contributor.authorJadidi-Niaragh, F
dc.contributor.authorBaradaran, B
dc.contributor.authorBabaloo, Z
dc.date.accessioned2018-08-26T04:56:10Z
dc.date.available2018-08-26T04:56:10Z
dc.date.issued2018
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/38455
dc.description.abstractInnate lymphoid cells (ILCs) are kind of innate immune cells which can be divided into three main subsets according to their cytokine release profile, transcription factors, and surface markers. ILCs affect the initial stages of immunity in response to microbes and participate in immunity, inflammation, and tissue repair. ILCs modulate immunity through resistance to the pathogens and regulation of autoimmune inflammation and metabolic homeostasis. Therefore dysregulation of ILCs may lead to chronic pathologies such as allergies (i.e., asthma), inflammation (i.e., inflammatory bowel disease), and autoimmunity (i.e., psoriasis, atopic dermatitis, rheumatoid arthritis, multiple sclerosis, and ankylosing spondylitis). Regarding the critical role of ILCs in the regulation of immune system, the elucidation of their function in different conditions makes an interesting target for improvement of novel therapeutic approach to modulate an immune response in different disease context.
dc.language.isoEnglish
dc.relation.ispartofJournal of cellular physiology
dc.titleThe role of innate lymphoid cells in health and disease.
dc.typearticle
dc.citation.volume233
dc.citation.issue6
dc.citation.spage4512
dc.citation.epage4529
dc.citation.indexPubmed
dc.identifier.DOIhttps://doi.org/10.1002/jcp.26250


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