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dc.contributor.authorShadjou, R
dc.contributor.authorHasanzadeh, M
dc.contributor.authorHeidar-Poor, M
dc.contributor.authorShadjou, N
dc.date.accessioned2018-08-26T04:54:38Z
dc.date.available2018-08-26T04:54:38Z
dc.date.issued2018
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/38184
dc.description.abstractAflatoxins are potential food pollutants produced by fungi. One of important toxins is aflatoxin M1 (AFM1). A great deal of concern is associated with AFM1 toxicity. In the present study, an innovative electrochemical interface for quantitation of AFM1 based on ternary signal amplification strategy was fabricated. In this work, silver nanoparticles was electrodeposited onto green and biocompatible nanocomposite containing ?-cyclodextrin as conductive matrix and graphene quantum dots as amplification element. Therefore, a multilayer film based on ?-cyclodextrin, graphene quantum dots, and silver nanoparticles was exploited to develop a highly sensitive electrochemical sensor for detection of AFM1. Fully electrochemical methodology was used to prepare a transducer on a glassy carbon electrode, which provided a high surface area toward sensitive detection of AFM1. The surface morphology of electrode surface was characterized by high-resolution field emission scanning electron microscope. The proposed sensing platform provides a simple tool for AFM1 detection. Under optimized condition, the calibration curve for AFM1 concentration was linear in 0.015mM to 25mM with low limit of quantification of 2?M. The practical analytical utility of the modified electrode was illustrated by determination of AFM1 in unprocessed milk samples.
dc.language.isoEnglish
dc.relation.ispartofJournal of molecular recognition : JMR
dc.titleElectrochemical monitoring of aflatoxin M1 in milk samples using silver nanoparticles dispersed on ?-cyclodextrin-GQDs nanocomposite.
dc.typearticle
dc.citation.volume31
dc.citation.issue6
dc.citation.spagee2699
dc.citation.indexPubmed
dc.identifier.DOIhttps://doi.org/10.1002/jmr.2699


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