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dc.contributor.authorJahed, M
dc.contributor.authorGhalichi, F
dc.contributor.authorFarhoudi, M
dc.date.accessioned2018-08-26T04:53:40Z
dc.date.available2018-08-26T04:53:40Z
dc.date.issued2018
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/37975
dc.description.abstractCircle of Willis (COW) is a network of cerebral artery which continually supplies the brain with blood. Any disturbance in this supply will result in trauma or even death. One of these damages is known as brain Aneurysm. Clinical methods for diagnosing aneurysm can only measure blood velocity; while, in order to understand the causes of these occurrences it is necessary to have information about the amount of pressure and wall shear stress, which is possible through computational models.In this study purpose is achieving exact information of hemodynamic blood flow in COW with an aneurysm and investigation of effective factors on growth and rupture of aneurysm.Here, realistic three-dimensional models have been produced from angiography images. Considering fluid-structure interaction have been simulated by the ANSYS.CFX software.Hemodynamic Studying of the COW and intra-aneurysm showed that the WSS and wall tension in the neck of aneurysms for case A are 129.5 Pa, and 12.2 kPa and for case B they are 53.3 Pa and 56.2 kPa, and more than their fundus, thus neck of aneurysm is prone to rupture.This study showed that the distribution of parameters was dependent on the geometry of the COW, and maximum values are seen in areas prone to aneurysm formation.
dc.language.isoEnglish
dc.relation.ispartofBio-medical materials and engineering
dc.titleFluid-structure interaction of patient-specific Circle of Willis with aneurysm: Investigation of hemodynamic parameters.
dc.typearticle
dc.citation.volume29
dc.citation.issue3
dc.citation.spage357
dc.citation.epage368
dc.citation.indexPubmed
dc.identifier.DOIhttps://doi.org/10.3233/BME-181732


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