| dc.description.abstract | Anesthesia in posterior teeth with Irreversible pulpitis harder than the other normal teeth. The aim of this study was to compare two kinds of anti-inflammatory medicines (dexamethasone and pharmapin) with a placebo according to their effects on the success rates of inferior alveolar nerve block (IANB) for endodontic treatment of mandibular molars with irreversible pulpitis. Methods: A total of 210 patients were divided into three groups of 70 patients each and were given a capsule of the same color and size (either a placebo of lactose powder, 400-mg pharmapin or 0.5-mg dexamethasone). After I hour of oral administration of the capsules, all the patients received standard IANB . In patients with successful IANB , the teeth were examined with cold pulp test; they were asked to assess their pain using the visual analog scale (VAS). Then, endodontic access cavity preparation was initiated . In case of pain during the treatment, the patients were asked to rate the pain on VAS . Success was defined as no or mold pain during treatment. Chi-squared test and ANOVA were used to compare qualitative and quantitative data between the groups. Results: No significant differences were found in sex and pretreatment pain between the patients in the three groups (p<0.981). The effect of Success of inferior alveolar nerve in teeth with irreversible pulpitis with 3 type of pro drug showed that the dexamethasone associated with a 51.4 % (less than 2.5). The Pharmapin was associated with 55.7% and Placebo was associated with 41.4 % . Conclusions: No significant differences were found in sex and pretreatment pain between the patients in the three groups (p<0.981). The effect of Success of inferior alveolar nerve in teeth with irreversible pulpitis with 3 type of pro drug showed that the dexamethasone associated with a 51.4 % (less that 2.5). The Pharmapin was associated with 55.7% and Placebo was associated with 41.4 % . The Chi-square test show that there is a signification deferens in the frequency of 3 type of drug(p=0.04). That rate of success of placebo group less than dexamethasone (p=0.041) and less than pharmapin (p=0.038) group but there are not significant difference between dexamethasone and pharmapin group (p=0.258). | |
