A comparative study on Benzydamin HCL 0.15% and Acetaminophen in pain reduction following soft tissue surgery

Abstract

Pain is a common complication after oral cavity surgeries. Different drugs have been introduced for pain relief. Benzidamine HCL bears analgesic and anesthetic effects without having any significant adverse effect. Therefore, this study aimed to compare the analgesic efficacy of Benzidamine HCL mouthrinse and acetaminophen in post-operative pain after soft tissue surgeries. Materials & Methods: In this study, 44 patints reffernig department of oral and maxillofacial surgery of Tabriz dental facultu were selected and divided into two groups randomly. In one group acetaminophen 500mg and in the other group Benzidamine HCL 0.15% was administrated. The pain severity was measures by visual analoge scale (VAS) by patients at 5, 12, and 24 hours after surgery. The collected data was analysed using Spss statistical software. Results: The reported pain levels after sugery in acetaminophen group were 11.1% without any pain, 64.4% with moderate and 24.4% with severe pain. In Benzidamine HCL group 8.8% without any pain, 41.4% with moderate and 29.8% with severe pain were the reported pain amounts. The X2 analysis revealed that the difference between groups in all intervals wasnEt significant (P>0.05). Conclusions: Based on the findings of this study, the analgesic efficacy of acetaminophen and benzidamine HCL was the same.