dc.description.abstract | Urbanized societies with transformation of the social structure, have increased energy consumption which causes numerous environmental problems. air pollution in urbanized reagions is a serious and permanent threat to the health of society and the environment. Epidemiological studies have shown a consistent relationship between air pollution and a lot of diseases. Materials and Method: 88 children (8 to 10 years old) enrolled in this cross-sectional study. 44 of them where from Tabriz and 44 of them where from Kaleibar; both in north -west Iran. Both group of study had the same socioeconomic status. Tabriz is a air polluted industrial city but Kaleibar is a rural small city with almost no air pollution. After selection of the cases, the saliva sample collected and transported to the laboratory. ELISA method was performed to detect Ig A level in the saliva. The difference between Ig A levels of two groups were analysed by independent t-test or equivalent nonparametric Mann-Whitney test and the software Spss 21. In this study, P value less than 0.05 was considered statistically significant. Results: The results of this study, show significant differences in the levels of salivary Ig A in children who live in two different regions. As salivary Ig A levels in children living Kaleibar (area with less air pollution)was higher than children who live in Tabriz (area with high air pollution). (P value = 0.001( Conculosion: the results of this study clearly indicate that the amount of salivary Ig A is reduced in air polluted regions which causes health problems in children. | |