A comparative study of the effect of double pedicle graft with and without plasma rich in growth factor (PRGF) in the treatment of class I & II gingival recessions

Abstract

previous researches have shown that Plasma rich in growth factors (PRGF) promote soft tissue healing. The purpose of this randomized controlled, clinical investigation was to evaluate the effect of double pedicle flaps (DPF) in root coverage with and without plasma rich in growth factors (PRGF). Materials & Methods: thirty pair sites in 15 patients with Miller class I and II recession were treated. In Test sites PRGF was used with DPF, while control sites were treated with DPF only. Under study Clinical parameters included: recession depth (RD), percentage of root coverage (RC), recession width (RW), attached gingival (AG), width of keratinized tissue (WKT), clinical attachment level (CAL), probing depth (PD). Patients were examined & evaluated after 1- 3 and 6 months post-surgery. All data were analyzed by SPSS15 and ANOVA (two ways). Results: Both of the treatment method led to significant improvement in the recession depth (RD), recession width (RW), clinical attachment level (CAL), keratinized tissue (WKT)and root coverage 6 months after surgery (p<0.001). While there was no significant difference after 6 months in the depth of pocket (PD) in two treatment groups compared to baseline. But, there was significant difference in RD, RW, CAL and root coverage, between the study & control group. Conclusions: based on the results of this study, DPF method with application of PRGF in root coverage procedure is more effective than the other method (DPF without PRGF).