Predictive value of biophysical profile in determining the immediate postpartum neonatal outcomes in preterm premature rupture of membranes (PPROM)

Abstract

Evaluating predictive value of BPP and Non-stress test (NST) in determining immediate postpartum neonatal outcomes in PPROM patients. In an analytic-descriptive study on 156 PPROM singleton pregnancies at gestational age of 34-37 weeks in Al-Zahra Center, Tabriz, during a 13-month period, BPP and NST were conducted on all patients before pregnancy termination. ABG analysis was conducted in all newborns, categorizing them into two groups: normal or abnormal (acidosis or alkalosis). Abnormal BPP was considered as total score <= 6. Predictive value of BPP and NST was evaluated accordingly. In predicting immediate postpartum neonatal outcome based on ABG results, sensitivity, specificity, positive/negative predictive values, and accuracy of BPP was 52.9%, 91.1%, 62.1%, 87.4% and 81.1%, respectively. There was a significant positive correlation between total BPP score and Apgar scores on minutes 1, 3 and 5. In the same circumstances, sensitivity, specificity, positive predictive/negative predictive values, and accuracy of NST was 50%, 89.3%, 56.7%, 86.5% and 80.8%, respectively. Mean Apgar scores on minutes 1, 3 and 5 were significantly higher in cases with reactive NST result. Based on our results, although there was a significant relationship between fetal outcome of mothers with PPROM, and BPP and NST results, these two modalities may not be efficient in predicting final fetal outcome due to low sensitivity. [Shabnam Jafari Zareh, Shamsi Abbasalizadeh, Fatemeh Abbasalizadeh, Omid Mashrabi. Predictive value of biophysical profile in determining the immediate postpartum neonatal outcomes in preterm premature rupture of membranes (PPROM). Life Sci J 2012;9(4):1420-1424] (ISSN:1097-8135). http://www.lifesciencesite.com. 217