Incidence and Prevalence of diabetes type 1: a systematic review and meta-analysis

Abstract

Introduction: Diabetes is a disease group characterized by high blood glucose levels due to impaired insulin production or activity. Type 1 diabetes is known as insulin-dependent diabetes and may be observed in all age groups; however, higher prevalence has been reported in children and young individuals. These patients are unable to produce sufficient insulin and includes 5-10% of whole diabetic population. In this type of diabetes βcell destruction is occurred in Langerhans islets which causes no insulin secretion. The aim of this study was to evaluate the global incidence and prevalence of type 1 diabetes mellitus. Materials and Methods: In this study the systematic review of the references was performed for global incidence and prevalence evaluation of type 1 diabetes mellitus. English papers were obtained from web of science (web of knowledge) google scholar, proquest, ovid, scopus, science direct and medline data bases from 1 January 1980 to 31 December 2019 and were screened based on title, abstract and whole document and the studies with our inclusion criteria were included in this study. Results: Our results indicated a global statistically significant 15/100000 and 9.5% incidence and prevalence, respectively.