School of Dentistry
Permanent URI for this communityhttps://dspace.tbzmed.ac.ir/handle/123456789/3
Tabriz Faculty of Dentistry is located in Tabriz, capital city of East Azarbayjan Province and is the only dental schoolwestern Iran.
Tabriz Dental School was founded in 1986. The first students entered in 1987, graduating in 1993. In 1997 the school moved into a new and modern building, covering 22,000 square meters.
The school expanded its educational programs in 2001 by offering its postgraduate specialty courses in three fields and at present it offers seven postgraduate specialty courses.
Prospects for the Future
We are determined, by asking for assistance from the Almighty, to promote the school's academic excellence, raise the standards of oral health in the community and join the circle of highly qualified dental schools in the country through optimizing instruction standards and innovative research programs.
Mission
Tabriz Faculty of Dentistry as the only dental school in the north-western Iran and as a part of a major university has combined and enjoyed the endeavors of competent and qualified academic staff with appropriate facilities and has committed itself to:
Training highly qualified general practitioners and specialists;
Updating the knowledge and skill of the graduates working in the north-western Iran;
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Item type: Item , Investigation of Remineralization effect of F-CaSiO4 incorporated Chitosan-Modified Persian gum hydrogels(Tabriz University of Medical Science, School of Dentistry, 2024) Doustdar, Zahra; Ghorbani, Marjan; Dentistry, Operative; Pournaghiazar, FatemehBackground: Regarding the high prevalence of dental caries all over the world, the control and prevention of this issue in the first steps have attracted a lot of attention. Dental caries initiate from the outer most layer of tooth, called enamel. Various materials have been introduced in the previous studies that can prevent mineral loss(Demineralization) and cause to the precipitation of minerals within the enamel(Remineralization). Chitosan and F-CaSiO4 are two of the mentioned materials. The aim of the present study is the investigation of the remineralization of F-CaSiO4 reinforced chitosan/modified Persian gum hydrogel. Methods: Eightteen Molar or Premolar extracted teethes were used in the current study. The crown of prepared teethes were divided into two parts in the mesiodistal direction. The obtained enamel blocks were classified into six groups in a way that each group was possess six samples. The initial hardness of samples were examined through the Vickers microhardness test by making three indentations in each sample. The surface of samples were coated by two layers of acid-resistant varnish. Meanwhile, the F-CaSiO4-filled hydrogel based on chitosan/modified Persian gum was prepared by the freeze-drying method. The first, second and third groups were not have any treating chemicals. The fourth, fifth, and sixth groups were treated using chitosan, F-CaSiO4, and CaSiO4-filled chitosan/Persian gum hydrogel, respectively. The treating chemical was put on the surface of each sample using a little brush. Thereafter, the samples were plunged into the demineralization solution as the first step of the pH cycle. After 3 h, the samples were withdrawn and immersed for 21 h in the remineralization solution. The explained cycle repeated for 5 days. Then, three different new indentations were created on the surface of each sample and the hardness of the samples were investigated by the Vickers microhardness test.The hardness difference before and after pH cycles is representative of lost minerals. The amount of lost phosphate in each group was calculated through Gas-Chromatography Mass technique. The morphological aspects of a sample of sixth group and the type of formed elements on its surface was evaluated by SEM and EDX techniques. Data comparison was done using ANCOVA test and SPSS software27. P<0.05 was considered significant. Results: The difference of microhardness values in group six before and after treatment (42.6±5.3) was lower than that of the control group (208.1±31.3 & 231.3±27.7), group four (142.1±24.1), and group five (113.6±19.5). There was a significant difference among microhardness values of group six and other groups (pvalue<0.05). Moreover, the loss of phosphate was lower in group six compared to other groups. The obtained FESEM images and EDX analysis also confirmed the presence of hydroxyapatite crystals on the surface of group six. Conclusions: According to the obtained results, it can be claimed that Persian gum modified chitosan with F-CaSiO4 additive can reduce the demineralization of tooth enamel. In addition, this hydrogel acts more effectively compared to neat Persian gum-modified chitosan hydrogel and neat F-CaSiO4 in reducing minerals’ loss from enamel.Item type: Item , Effect of addition of bioactive glass (SiO2–CaO–P2O5–MgO-SrO) to glass ionomer and resin modified glass ionomer cement on dentin remineralization(Tabriz University of Medical Sciences, School of Dentistry, 2023) Nasiri, Ayda; Daneshpouy, Mahdi; Operative dentistry; Rezaei, YasharIntrudoction: Bioactive glass is a material with high biocompatibility, which by creating a biological response on its surface, causes the formation of a bond between itself and tissues. Due to its unique properties, in recent years, extensive studies have been conducted on the use of this substance in dentistry. Glass ionomers have many advantages, such as direct bonding with teeth, which allow effective restoration of decayed teeth. In addition, they have good biocompatibility properties, release and absorb fluoride, resulting in an antibacterial effect and fluorapatite remineralization. Unlike composites, their shrinkage during setting is also negligible. But despite their major advantages compared to other common restorative materials, their mechanical properties are still improving since their development. Considering the lack of studies in the field of adding bioactive glass to resin modified glass ionome, this study was conducted with the aim of investigating dentin remineralization by adding bioactive glass to glass ionomer. Materials and Methods: 30 premolars without decay were collected and then placed in thymol solution for one month for disinfection and then kept in saline solution at room temperature until the time of study. The surface enamel of the premolars was removed with a diamond disc and air spray, and the dentin was demineralized with ethyldiamine tetraacetic acid solution for 6 hours. The samples were randomly divided into 6 experimental groups based on the amount of bioactive glass and the type of glass ionomer, and each group contained 5 permolar: the first group contained glass ionomer in pure form, the second group contained ten percent of weight, and the third group contained twenty percent of weight bioactive glass. For resin modified glass ionomer, three groups were formed in the same way. The sol-gel method was used for the synthesis of bioactive glass. Glass ionomer powder and resin glass ionomer were mixed with bioactive glass separately for two minutes by ball milling. Then their powder and liquid were mixed according to the factory instructions. The mixed glass ionomer was poured into a mold to form a block. Then the blocks were approximated to the surface of the demineralized dentin, secured by orthodontic bands and kept in artificial saliva for two weeks. After this period, the blocks were separated and the surface of the dentin was washed with distilled water for 3 minutes. XRD and SEM tests were performed three times on the samples. Once before demineralizing the dentin, once after demineralizing the dentin, and the last time after keeping it in artificial saliva for two weeks, the test was performed on the samples and the remineralization of the dentin was checked. Results: In XRD analysis of the dentine surface, before and after contact with BAG, peaks are observed that indicate FAP and HAP crystals. These peaks decreased significantly after demineralization. In BAG20 groups, these peaks increased the most after contact. In statistical studies, the effect of time did not have a significant difference in the angle of 26, but it was significant in the angle of 32. The group effect was statistically significant (p-value<0.001) and GI20 and RMGI20 groups showed the most changes and GI0 and RMGI0 groups showed the least changes. The difference in remineralization between GI and RMGI was not statistically significant. Conclusion: Use of bioactive glass in weight percentages of 10 and 20 with glass ionomer and modified glass ionomer resin is effective in the process of dentin remineralization, and with the increase in the percentage of bioactive glass, the ability of dentin remineralization increases. There is no significant difference between the remineralization ability of GI and RMGI modified with bioactive glass.Item type: Item , Effect of Sol-Gel-Derived SiO2–CaO–P2O5–MgO-SrO Bioactive glass on Remineralizing of Early Enamel Lesions(Tabriz University of Medical Sciences, School of Dentistry, 2023) Nesabi, Mahyar; Daneshpouy, Mahdi; Riyahifar, Sevda; Dental Biomaterial; Rezaei, YasharBackground: Due to the nano structure, bioactive glasses can be effective in remineralization of tooth enamel. The aim of this study was to investigate the effect of synthesized bioactioglass on the remineralization rate and morphology of the damaged enamel surface. Materials and Methods: In this study, 72 third molar of human teeth that were free of caries and fillings were selected. After extraction, the teeth were disinfected by placing them in thymol solution for one week. Then the crown of the teeth was cut longitudinally by a cutting machine with a thickness of about 2 mm and it was placed in the ultrasonic machine for 10 minutes to remove debris. All samples were etched by 37% phosphoric acid for 2 minutes. A suspension with a concentration of 20% was prepared on 36 of the samples from synthesized bioactioglass powder and applied for 15 days (10 minutes per day) and placed in the ultrasonic machine for 3 minutes. The remaining 36 samples (control) were only placed in the ultrasonic device. To study the created coating, the samples were examined by SEM, XRD, ATR-FTIR and microhardness tests. The data were statistically analyzed with GraphPad Prism 9.5.0 software and ANOVA, Bonferroni statistical tests. Results: The samples showed a significant decrease in microhardness after demineralization. The microhardness of remineralized teeth was significantly higher than that of demineralized teeth (P < 0.001). The XRD test results (theta=26,32 in both cases) did not show a significant difference in the degree of mineralization of the studied groups. The ATR-FTIR test results in V3PO4 was not significantly different in three groups. However, ATR-FTIR in V1PO4 showed the mineralization rate in the control group (tooth without caries) significantly higher than the caries and restoration groups (P < 0.001). Conclusion: Application of synthesized bioactive glass increased microhardness during enamel mineralization process.