Thyroid hormones status during pregnancy in normal Iranian women
MetadataShow full item record
Pregnancy is associated with significant, but reversible changes in thyroid function studies, which are among the most profound seen as a result of a normal physiologic state. The present study was carried out to find out alterations in thyroid function tests in each trimester in normal pregnant women as compared to non-pregnant women in Tabriz-Iran. A case-control study designed with 229 normal pregnant women that randomly selected from the first (64 samples), the second (92 samples), and the third (73 samples) trimesters and 250 randomly selected non-pregnant healthy female controls. Age range in both groups was 16-40 years. Thyroid function tests carried out by measuring serum levels of thyroid stimulating hormone (TSH), free and total thyroxin (FT 4, TT4), and free and total triiodothyronine (FT 3, TT3) by commercially available radio immunoassay kits. We found that mean TT4 increased progressively during pregnancy. Our study showed increasing in serum levels of TT3 in the second trimester and then declining during the third trimester compared with non-pregnant women. We showed that FT4 strongly decreased during the third trimester. Free T3 showed declining in the second and third trimesters. Mean TSH did not show significant difference in each trimester compared with non-pregnant women. The thyroid function tests in pregnancy should be interpreted against gestational age-related reference intervals to avoid mis-interpretation of thyroid function during pregnancy.
Showing items related by title, author, creator and subject.
Multicenter screening for adverse pregnancy outcomes by uterine artery doppler in the second and third trimester of pregnancy Jamal, A; Abbasalizadeh, F; Vafaei, H; Marsoosi, V; Eslamian, L (2013)Aims: Increased uterine artery pulsatility index (PI) is associated with adverse pregnancy outcomes. The aim of the study was to determine the role of uterine artery PI at 18-24 and 30-34 weeks, gestation in predicting ...
Assessment of intertrimester and seasonal variations of urinary iodine concentration during pregnancy in an iodine-replete area Ainy, E; Ordookhani, A; Hedayati, M; Azizi, F (2007)Objective: To assess intertrimester and seasonal variations in urinary iodine concentration (UIC) among pregnant women. Patients and measurements: Pregnant Tehranian women, with no history of thyroid ablation or consumption ...
Fardiazar, Z; Derakhshan, I; Torab, R; Vahedi, A; Goldust, M (2014)In this study maternal and neonatal outcome evaluated in each trimester of pregnancies with non obstetric laparotomies. In this descriptive-analytic study, 100 pregnant women operated during pregnancy were evaluated. Based ...