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dc.contributor.authorAzizi, M
dc.contributor.authorBahrieniain, SA
dc.contributor.authorBaghdasarians, A
dc.contributor.authorEmamipur, S
dc.contributor.authorAzizmohammadi, Z
dc.contributor.authorQutbi, SM
dc.contributor.authorJavadi, H
dc.contributor.authorAssadi, M
dc.contributor.authorAsli, IN
dc.date.accessioned2018-08-26T09:41:34Z
dc.date.available2018-08-26T09:41:34Z
dc.date.issued2014
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/58484
dc.description.abstractObjective: The purpose of this study is to investigate the impact of cognitive group therapy and happiness training objectively in the local cerebral blood flow of patients with major depression (MD). Patients, material, methods: The present research is semi-experimental to pre- and post-test with a control group. Three groups were formed, and this number was incorporated in each group: 12 patients were chosen randomly; the first group of depressed patients benefited from the combination of pharmacotherapy and sessions of cognitive group therapy; the second group used a combination of pharmaco-therapy and sessions of happiness training; and a third group used only pharmacother-apy. We compared cognitive-behavioural therapy and happiness training efficacy with only pharmacotherapy in MD patients. We performed brain perfusion SPECT in each group, before and after each trial. Results: The study was conducted on 36 patients with MD (32 women and 4 men; mean age: 41.22 آ± 9.08; range: 27-65 years). There were significant differences regarding the two trial effects into two experimental groups (p < 0/001) before and after trials, while such differences were not significant in the control group (p > 0.05). In addition, there was significant difference among the regional cerebral blood flow in the frontal and prefrontal regions into two experimental groups before and after trials (p < 0/001), while such differences were not significant in the control group (p > 0.05). Conclusion: This study demonstrated decreased cerebral perfusion in the frontal regions in MD patients, which increased following cognitive group therapy and happiness training. Because of its availability, low costs, easy performance, and the objective semi-quantitative information supplied, brain perfusion SPECT scanning might be useful to assess the diagnosis and therapy efficacy. Further exploration is needed to validate its clinical role. é Schattauer 2014.
dc.language.isoEnglish
dc.relation.ispartofNuklearMedizin
dc.subjectsertraline
dc.subjecttechnetium 99m
dc.subjectcysteine
dc.subjectcysteine ethyl ester tc 99m
dc.subjectradiopharmaceutical agent
dc.subjecttechnetium complex
dc.subjectadult
dc.subjectaged
dc.subjectArticle
dc.subjectBeck Depression Inventory
dc.subjectbrain blood flow
dc.subjectbrain perfusion
dc.subjectclinical article
dc.subjectcognitive group therapy
dc.subjectcontrolled study
dc.subjectfemale
dc.subjectfollow up
dc.subjecthappiness training
dc.subjecthuman
dc.subjectmajor depression
dc.subjectmale
dc.subjectoxford happiness inventory
dc.subjectpost hoc analysis
dc.subjectpsychologic test
dc.subjectpsychotherapy
dc.subjectrandomized controlled trial
dc.subjectsingle photon emission computer tomography
dc.subjectanalogs and derivatives
dc.subjectblood flow velocity
dc.subjectbrain
dc.subjectbrain circulation
dc.subjectcognitive therapy
dc.subjectDepressive Disorder, Major
dc.subjectdiagnostic use
dc.subjectgroup therapy
dc.subjecthappiness
dc.subjectpathophysiology
dc.subjectprocedures
dc.subjectscintigraphy
dc.subjectscintiscanning
dc.subjectsingle photon emission computer tomography
dc.subjecttreatment outcome
dc.subjectAdult
dc.subjectBlood Flow Velocity
dc.subjectBrain
dc.subjectCerebrovascular Circulation
dc.subjectCognitive Therapy
dc.subjectCysteine
dc.subjectDepressive Disorder, Major
dc.subjectFemale
dc.subjectHappiness
dc.subjectHumans
dc.subjectMale
dc.subjectOrganotechnetium Compounds
dc.subjectPerfusion Imaging
dc.subjectPsychotherapy, Group
dc.subjectRadiopharmaceuticals
dc.subjectTomography, Emission-Computed, Single-Photon
dc.subjectTreatment Outcome
dc.titleThe role of cognitive group therapy and happiness training on cerebral blood flow using 99mTc-ECD brain perfusion SPECT: A quasi-experimental study of depressed patients(Article) [Die wirkung der kognitiven gruppentherapie und des glückstrainings auf die zerebrale durchblu-tung mittels 99mTc-ECD hirndurchblutungs-SPECT eine quasi-experimentelle studie an depressiven patienten]
dc.typeArticle
dc.citation.volume53
dc.citation.issue5
dc.citation.spage205
dc.citation.epage210
dc.citation.indexScopus
dc.identifier.DOIhttps://doi.org/10.3413/Nukmed-0632-13-11


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