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Profile and frequency of p53 Gene alterations in gastritis lesions from Iran
Background: It has been frequently shown that p53 alterations have an important role in the development of gastric cancers but there is no data on p53 alteration in gastric cancer and its precancerous lesions from Iran ...
Relation between demographic factors and hospitalization in patients with gastrointestinal disorders, using quantile regression analysis.
OBJECTIVE: The aim of this study is to investigate relation between demographic factors and hospitalization in gastrointestinal disorders. Quantile regression was used to analyze the predictors of duration of staying in ...
Association between the 1793G>A MTHFR polymorphism and sporadic colorectal cancer in Iran
Background: It has been proposed that folate and polymorphisms of the enzyme methylenetetrahydrofolate reductase (MTHFR), which regulates influx of folate for methylation reactions for DNA synthesis and repair, are involved ...
Impact of EXO1 polymorphism in susceptibility to colorectal cancer
Background and Aim: One candidate gene for colorectal cancer (CRC) susceptibility is exonuclease 1 (EXO1). It is a member of RAD2 nuclease family, which plays a major role in mismatch repair, DNA replication, and recombination. ...
Direct and indirect medical costs of functional constipation: A population-based study
Background Constipation causes a large number of medical visits each year and imposes significant financial toll on healthcare systems worldwide. So the present communitybased study was conducted in order to estimate ...
Association between MTHFR polymorphism (C677T) with nonfamilial colorectal cancer
The enzyme 5,10-methylene-tetrahydrofolate reductase (MTHFR) is linked to DNA methylation, synthesis, and repair. C677T is one of the most important polymorphisms in the MTHFR gene. The single nucleotide polymorphism C677T ...