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Tumor necrosis factor-alpha gene promoter polymorphism in Iranian patients with chronic hepatitis B
(2006)
Background: Clearance of hepatitis B virus (HBV) infection requires a good host immune response. Cytokines like tumor necrosis factor-alpha (TNF-?) may play a role in such immune response. Genetic changes in TNF-? gene ...
Frequency of three common mutations of CARD15/NOD2 gene in Iranian IBD patients
(2008)
Background: The CARD15/NOD2 gene, located on the pericentromeric region of chromosome 16 (IBD 1) has been reported to have an association with IBD, especially Crohn's disease. Three common mutations of CARD15 are variably ...
Appendectomy, tonsillectomy, and risk of inflammatory bowel disease: A case control study in Iran
(2006)
There is some controversy about the prevalence of appendectomy and tonsillectomy among patients with Crohn's disease and a lower rate of appendectomy among patients with ulcerative colitis (UC). The objective of this study ...
NOD2 exonic variations in Iranian Crohn's disease patients
(2011)
Purpose The NOD2 gene is known to have a strong association with Crohn's disease, but different trends were reported in occurrence of NOD2 variants in distinct ethnicities. The aim of this study was to assess all exonic ...