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siRNA-mediated silencing of survivin inhibits proliferation and enhances etoposide chemosensitivity in acute myeloid leukemia cells.

Karami, H; Baradaran, B; Esfahani, A; Estiar, MA; Naghavi-Behzad, M; Sakhinia, M; Sakhinia, E (2013)

Overexpression of survivin, a known inhibitor of apoptosis, is associated with tumor progression and drug resistance in numerous malignancies, including leukemias. The aim of this study was to investigate the effect of a ...