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siRNA-mediated silencing of survivin inhibits proliferation and enhances etoposide chemosensitivity in acute myeloid leukemia cells. 

Karami, H; Baradaran, B; Esfahani, A; Estiar, MA; Naghavi-Behzad, M; Sakhinia, M; Sakhinia, E (2013)
Overexpression of survivin, a known inhibitor of apoptosis, is associated with tumor progression and drug resistance in numerous malignancies, including leukemias. The aim of this study was to investigate the effect of a ...
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Down-regulation of Mcl-1 by small interference RNA induces apoptosis and sensitizes HL-60 leukemia cells to etoposide. 

Karami, H; Baradaran, B; Esfehani, A; Sakhinia, M; Sakhinia, E (2014)
Acute myeloid leukemia (AML) is a fatal hematological malignancy which is resistant to a variety of chemotherapy drugs. Myeloid cell leukemia-1 (Mcl-1), a death-inhibiting protein that regulates apoptosis, has been shown ...

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Author
Baradaran, B (2)
Karami, H (2)
Sakhinia, E (2)
Sakhinia, M (2)Esfahani, A (1)Esfehani, A (1)Estiar, MA (1)Naghavi-Behzad, M (1)Subject
Antineoplastic Agents, Phytogenic (2)
Apoptosis (2)
Blotting, Western (2)
Cell Proliferation (2)
Etoposide (2)Gene Expression Regulation, Neoplastic (2)
Humans (2)
Real-Time Polymerase Chain Reaction (2)Reverse Transcriptase Polymerase Chain Reaction (2)RNA, Messenger (2)... View MoreDate Issued2013 (1)2014 (1)Has File(s)
No (2)

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