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8-OH-DPAT (5-HT1A agonist) attenuates 6-Hydroxy- dopamine-induced catalepsy and modulates inflammatory cytokines in rats
(2013)
Objective(s): Neuroinflammation in Parkinson disease (PD) is associated with glial cells activation and production of different inflammatory cytokines. In this study, we investigated the effect of chronic administration ...
5-HT 1A receptor activation improves anti-cataleptic effects of levodopa in 6-hydroxydopamine-lesioned rats
(2011)
Background and the purpose of the study: In Parkinsons disease (PD) prolong use of L-DOPA causes some motor disorders such as wearing-off and L-DOPA induced dyskinesia (LID). In this investigation the effect of 8-OHDAPT, ...
99m Tc-MIBI scintigraphy versus 131I whole body scan in the follow-up of patients with differentiated thyroid carcinoma
(2006)
Thyroid cancer is the most common endocrine malignancy. More than 90% of primary thyroid cancers are papillary or follicular types, together termed Differentiated Thyroid Cancers (DTC. The aim of this study was to assess ...
64-Slice multidetector computed tomographic angiography and invasive coronary angiography in diagnosis of significant coronary artery stenosis
(2012)
Introduction: Introduction of 64-slice multidetector computed tomography (MDCT) has resulted in a great improvement of the non-invasive coronary artery imaging. The present study aimed to evaluate the diagnostic accuracy ...
A comparison of preoperative ondansetron and dexamethasone in the prevention of post-tympanoplasty nausea and vomiting
(2012)
Background: Nausea and vomiting are common complications of anesthesia and surgery. Patients undergoing tympanoplasty are exposed to a higher risk of postoperative nausea vomiting (PONV). These complications may alter the ...
A multicenter study to evaluate the safety and efficacy of Heberon (interferon alfa-2b) in combination with ribavirin for the treatment of chronic hepatitis C in Iran
(2005)
Background: Combination therapy with interferon and ribavirin is the most effective treatment for chronic hepatitis C today. The aim of this study was to evaluate the efficacy and safety of thrice-weekly Heberon (interferon ...
A new diagnostic sign for rheumatoid arthritis: Avicenna sign
(2004)
Aim: The status of a new sign for diagnosing rheumatoid arthritis is discussed for the first time in this study. It is defined as marked tenderness on the anterior surface of leg (shin) on pressure of about 4 kg by thumb. ...
A morphometeric magnetic resonance imaging study of age and gender-related volumetric changes of putamen nucleus in healthy humans
(2010)
Introduction: The purpose of this study was to determine the age, sex, and hemispheric differences in volume of the human putamen nucleus in right-handed healthy humans. Materials and Methods: This study was performed on ...
A phase III, randomized, two-armed, double-blind, parallel, active controlled, and non-inferiority clinical trial to compare efficacy and safety of biosimilar adalimumab (CinnoRAآ®) to the reference product (Humiraآ®) in patients with active rheumatoid arthritis
(2017)
Background: This study aimed to compare efficacy and safety of test-adalimumab (CinnoRAآ®, CinnaGen, Iran) to the innovator product (Humiraآ®, AbbVie, USA) in adult patients with active rheumatoid arthritis (RA). Methods: ...
A randomized, double-blind, placebo-controlled study to evaluate the role of formoterol in the management of acute asthma
(2007)
Aim: To evaluate the efficacy and tolerability of formoterol delivered by Aerolizer in the emergency department. Methods: A single-centre, double-blind, randomised, placebo-controlled, parallel group study was conducted ...