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The effect of moisture on the compaction properties of the binary mixture of hydroxypropylmethyl cellulose K4M/ibuprofen
(1998)
The consolidation and compaction properties of hydroxypropylmethyl cellulose K4M and ibuprofen containing various moisture contents were evaluated. The powders were compressed using a high-speed compaction simulator. The ...
The role of various surfactants and fillers in controlling the release rate of theophylline from HPMC matrices
(1999)
The effect of lactose, NaCMC and various surfactants, i.e. sodium lauryl sulfate, cetyltriammonium bromide, Arlacel 60 and Tween 80 on the release rate of theophylline from HPMC matrices was evaluated. The results showed ...
The compaction properties of mixtures of ibuprofen and hydroxypropylmethyl cellulose
(1998)
The consolidation and compaction properties of hydroxypropylmethyl cellulose K4M and ibuprofen, and their binary mixtures were evaluated. Powders were compressed using a high-speed compaction simulator at different compression ...
Effects of hydrophilic excipients and compression pressure on physical properties and release behavior of aspirin-tableted microcapsules
(1999)
Aspirin ethylcellulose microcapsules were tableted by compression with or without excipients (lactose or polyvinylpyrrolidone [PVP]). The effects of the amount of the excipients and microcapsule size on the crushing strength ...
Effect of polysorbates on atenolol release from film-coated tablets
(1999)
The effects of different concentrations of various polysorbates on the release rate of atenolol from film-coated tablets were evaluated. The release profile of atenolol showed that increasing the concentration of polysorbate ...
An approach to controlled-release dosage form of propranolol hydrochloride
(2000)
It is possible to release a drug with only limited diffusion from a membrane-coated system using osmotic pumping. In this study, a propranolol osmotic pump was produced by coating the core tablets with cellulose acetate. ...
Studies on controlled-release formulations of diclofenac sodium
(1997)
The effects of various polymers on the release of diclofenac sodium from their matrices have been evaluated. In vitro release profiles of diclofenac sodium from ethylcellulose and hydroxypropylmethylcellulose (HPMC) K4M ...
A review on the methods of preparation of pharmaceutical nanoparticles
(2009)
Objectives: Nanotechnology will affect human being life impressively over the next decade in different fields, including medicine and pharmacy. Polymeric nanoparticles have been far and wide studied as particulate carriers ...
Agglomeration of celecoxib by quasi-emulsion solvent diffusion method without stabilizer: effect of good solvent
(2017)
Aim: The aim of the present research is to investigate the feasibility of agglomeration of crystals by the quasi-emulsion solvent diffusion method without using a stabilizer. Method: Two solvent systems comprising a solvent ...
An in Vitro aerosolization efficiency comparison of generic and branded Salbutamol metered dose inhalers
(2017)
Background: Due to the high rate of pulmonary diseases, respiratory drug delivery systems have been attracted excessive attention for the past decades. Because of limitations and growing drug bill, physicians are encouraged ...