Now showing items 11-20 of 2042
Inhibition of c-REL using siRNA increased apoptosis and decreased proliferation in pre-B ALL blasts: Therapeutic implications
The c-Rel transcription factor is a unique member of the NF-kB family that has a role in apoptosis, proliferation and cell survival. Overexpression of c-Rel is detected in many human B cell tumors, including B-cell leukemia ...
Clinical Significance of ST Elevation in Lead aVR in Acute Pulmonary Embolism.
Prognostic stratification of patients with acute pulmonary embolism (PTE) is crucial in identifying patients who would benefit from more aggressive treatment. We aimed to examine the value of ST elevation in lead aVR (STEaVR ...
The effect of oral evening primrose oil on menopausal hot flashes: A randomized clinical trial
Purpose: Hot flashes are common experience for menopausal women, and for many, are severe enough to significantly compromise their overall sense of well being and quality of life. The aim of this study was to compare the ...
Prevalence of atherosclerosis in patients with inactive rheumatoid arthritis
Patients with rheumatoid arthritis (RA) exhibit higher cardiovascular morbidity and mortality than the general population. The common carotid artery intima-media thickness (CCA-IMT) measured by ultrasound is a validated ...
Women with congenital factor VII deficiency: clinical phenotype and treatment options from two international studies.
A paucity of data exists on the incidence, diagnosis and treatment of bleeding in women with inherited factor VII (FVII) deficiency.Here we report results of a comprehensive analysis from two international registries of ...
Resistance to single-agent chemotherapy and its risk factors in low-risk gestational trophoblastic neoplasms
Aim Gestational trophoblastic neoplasm (GTN) is a rare disease which is classified into high- and low-risk groups. While the high-risk patients require combination therapy, the low-risk groups respond to single-agent ...
Involvement of PPAR-gamma and p53 in DHA-induced apoptosis in Reh cells.
Docosahexaenoeic acid (DHA, 22:6 n-3) is an omega-3 polyunsaturated fatty acid that is found in fish oil and exerts cytotoxic effect on a variety of cell lines. The molecular target, responsible for mediating this effect ...
Letter: Comment on "Can Serum Glucose Level in Early Admission Predict Outcome in Patients with Severe Head Trauma?"
[No abstract available]
Response of human T cells to tetanus neurotoxin H<inf>CC</inf> Sub-Domain: T cell cytokine production and activation marker induced by H<inf>CC</inf>
Tetanus is caused by the tetanus neurotoxin (TeNT), a 150 kDa single polypeptide molecule which is cleaved into active two-chain molecules composed of a 50 kDa N-terminal light (L) and a 100 kDa C-terminal heavy (H) chains. ...