Now showing items 11-20 of 27
Association between the 1793G>A MTHFR polymorphism and sporadic colorectal cancer in Iran
Background: It has been proposed that folate and polymorphisms of the enzyme methylenetetrahydrofolate reductase (MTHFR), which regulates influx of folate for methylation reactions for DNA synthesis and repair, are involved ...
Improvement of liver function in liver cirrhosis patients after autologous mesenchymal stem cell injection: A phase I-II clinical trial
BACKGROUND: End-stage liver disease is a medical problem with high morbidity and mortality. We have investigated the feasibility, safety, and efficacy of using autologous mesenchymal stem cells (MSCs) as a treatment. ...
Prenatal screening and counseling in iran and ethical dilemmas
Objective: Prenatal screening has become an increasingly common procedure all over the world. It offers couples useful information relating to the health of their fetus, although it faces us with serious ethical dilemmas ...
FBXW7/hCDC4 is a general tumor suppressor in human cancer
The ubiquitin-proteasome system is a major regulatory pathway of protein degradation and plays an important role in cellular division. Fbxw7 (or hCdc4), a member of the F-box family of proteins, which are substrate recognition ...
Age-specific seroprevalence of hepatitis A infection among children visited in pediatric hospitals of Tehran, Iran
Background: Hepatitis A is an enterically transmitted disease that still remains endemic in many developing countries. In some countries improvements in living conditions have recently led to changing in epidemiology of ...
Glutathione-S-transferase M1, T1 and P1 gene polymorphisms in type I autoimmune hepatitis: A case-control study 
[No abstract available]
Gastro-esophageal reflux symptoms and body mass index: No relation among the Iranian population
An association between obesity and symptoms of gastro-esophageal reflux disease (GERD) has been frequently reported in western societies. A recent study indicated a consistent association between abdominal diameter and ...
Gastro-oesophageal reflux disease and irritable bowel syndrome: A significant association in an Iranian population
Background: Gastro-oesophageal reflux disease and irritable bowel syndrome are common diseases, which may be related. Aim: To assess the association between gastro-oesophageal reflux disease and irritable bowel syndrome ...
Four novel germline mutations in the MLH1 and PMS2 mismatch repair genes in patients with hereditary nonpolyposis colorectal cancer
Background: Hereditary nonpolyposis colorectal cancer (HNPCC) is the most common cause of early onset hereditary colorectal cancer. In the majority of HNPCC families, microsatellite instability (MSI) and germline mutation ...
Frequency of three common mutations of CARD15/NOD2 gene in Iranian IBD patients
Background: The CARD15/NOD2 gene, located on the pericentromeric region of chromosome 16 (IBD 1) has been reported to have an association with IBD, especially Crohn's disease. Three common mutations of CARD15 are variably ...