Now showing items 1-10 of 26
Device-associated infection rates and bacterial resistance in six academic teaching hospitals of Iran: Findings from the International Nocosomial Infection Control Consortium (INICC)
Device-associated health care-acquired infections (DA-HAIs) pose a threat to patient safety, particularly in the intensive care unit (ICU). However, few data regarding DA-HAI rates and their associated bacterial resistance ...
Direct and indirect medical costs of functional constipation: A population-based study
Background Constipation causes a large number of medical visits each year and imposes significant financial toll on healthcare systems worldwide. So the present communitybased study was conducted in order to estimate ...
FBXW7/hCDC4 is a general tumor suppressor in human cancer
The ubiquitin-proteasome system is a major regulatory pathway of protein degradation and plays an important role in cellular division. Fbxw7 (or hCdc4), a member of the F-box family of proteins, which are substrate recognition ...
Four novel germline mutations in the MLH1 and PMS2 mismatch repair genes in patients with hereditary nonpolyposis colorectal cancer
Background: Hereditary nonpolyposis colorectal cancer (HNPCC) is the most common cause of early onset hereditary colorectal cancer. In the majority of HNPCC families, microsatellite instability (MSI) and germline mutation ...
Glutathione-S-transferase M1, T1 and P1 gene polymorphisms in type I autoimmune hepatitis: A case-control study 
[No abstract available]
Gastro-oesophageal reflux disease and irritable bowel syndrome: A significant association in an Iranian population
Background: Gastro-oesophageal reflux disease and irritable bowel syndrome are common diseases, which may be related. Aim: To assess the association between gastro-oesophageal reflux disease and irritable bowel syndrome ...
Age-specific seroprevalence of hepatitis A infection among children visited in pediatric hospitals of Tehran, Iran
Background: Hepatitis A is an enterically transmitted disease that still remains endemic in many developing countries. In some countries improvements in living conditions have recently led to changing in epidemiology of ...
Appendectomy, tonsillectomy, and risk of inflammatory bowel disease: A case control study in Iran
There is some controversy about the prevalence of appendectomy and tonsillectomy among patients with Crohn's disease and a lower rate of appendectomy among patients with ulcerative colitis (UC). The objective of this study ...
Association between MTHFR polymorphism (C677T) with nonfamilial colorectal cancer
The enzyme 5,10-methylene-tetrahydrofolate reductase (MTHFR) is linked to DNA methylation, synthesis, and repair. C677T is one of the most important polymorphisms in the MTHFR gene. The single nucleotide polymorphism C677T ...
Knowledge of disease and health information needs of the patients with inflammatory bowel disease in a developing country
Background and aims: This study was performed to have a first-time assessment on the knowledge level of a population of inflammatory bowel disease (IBD) patients in a developing country like Iran and to identify their ...