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A phase III, randomized, two-armed, double-blind, parallel, active controlled, and non-inferiority clinical trial to compare efficacy and safety of biosimilar adalimumab (CinnoRAآ®) to the reference product (Humiraآ®) in patients with active rheumatoid arthritis
(2017)
Background: This study aimed to compare efficacy and safety of test-adalimumab (CinnoRAآ®, CinnaGen, Iran) to the innovator product (Humiraآ®, AbbVie, USA) in adult patients with active rheumatoid arthritis (RA). Methods: ...
A socio-cognitive inquiry of excessive mobile phone use
(2014)
Objectives: The study examined the predictive ability of selected demographic and socio-psychological characteristics in explaining excessive mobile phone use (EMPU) behavior and problematic use in a sample of university ...
Association between admission neutrophil to lymphocyte ratio and outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease [Kronik obstrأ¼ktif akci?er hastal??? alevlenme olgular?nda ba?vuru n?trofil lenfosit oran? ile prognoz aras?ndaki ili?ki]
(2017)
Association between admission neutrophil to lymphocyte ratio and outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease Introduction: The prognostic significance of neutrophil-to-lymphocyte ...
Association of UCP2 -866G>A polymorphism with nonalcoholic fatty liver disease in patients from North-West of Iran
(2017)
Objective: To investigate the association of uncoupling protein-2 (UCP2) -866G>A gene polymorphism (rs659366) with nonalcoholic fatty liver disease (NAFLD). Methods: We performed a case-control study with a cohort of 75 ...
A Novel Combination of Docosahexaenoic Acid, All-Trans Retinoic Acid, and 1, 25-Dihydroxyvitamin D3 Reduces T-Bet Gene Expression, Serum Interferon Gamma, and Clinical Scores but Promotes PPAR? Gene Expression in Experimental Autoimmune Encephalomyelitis
(2016)
Vitamins are immunologically interesting due to their significant immunomodulatory activities. Experimental autoimmune encephalomyelitis (EAE) is one of the most commonly used experimental models for studying autoimmune ...
A novel monoclonal antibody against a synthetic peptide from ?-actin can react with its corresponding protein
(2015)
Actin is one of the most widely studied structural and multifunctional housekeeping proteins in eukaryotic cells with important roles in many cell functions. Antibodies against ?-actin and other housekeeping gene-encoded ...
Aldehyde and xanthine oxidase activities in tissues of streptozotocin- induced diabetic rats: Effects of vitamin e and selenium supplementation
(2012)
Effects of vitamin E and selenium supplementation on aldehyde oxidase (AO) and xanthine oxidase (XO) activities and antioxidant status in liver, kidney, and heart of streptozotocin (STZ)-induced diabetic rats were examined. ...
Association of endothelial nitric oxide synthase gene variants (-786 T>C, intron 4 b/a VNTR and 894 G>T) with idiopathic recurrent pregnancy loss: A case-control study with haplotype and in silico analysis
(2017)
Objective(s) Many lines of evidence suggest that reduced production of nitric oxide (NO) due to single nucleotide polymorphisms in endothelial nitric oxide synthase (eNOS) gene may affect the implantation and maintenance ...
Association of P53 (?16ins-Pro) Haplotype with the Decreased Risk of Differentiated Thyroid Carcinoma in Iranian-Azeri Patients
(2015)
Association of P53 polymorphisms with the increased risk of various cancers has been investigated in numerous studies. However, the results were conflicting and no polymorphism has been determined as a definite risk factor. ...
?-Tocopherol supplementation reduces biomarkers of oxidative stress in children with Down syndrome: A randomized controlled trial
(2014)
Background:Down syndrome (DS) is the most common human chromosomal abnormality. It is characterized by mental retardation and several metabolic disturbances, including elevated oxidative stress, which may be causally linked. ...