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Prognostic factors in 1,138 Iranian colorectal cancer patients
(2008)
Background and aim: The incidence of colorectal cancer is increased in Iran in recent years and colorectal cancer is the fourth most common cancer in both sexes. The aim of this study is to define the prognostic factors ...
Insulin resistance in chronic hepatitis B and C
(2006)
Aim: To determine whether insulin resistance occurs in patients with chronic hepatitis B (CHB) and chronic hepatitis C (CHC), and its relationship with the presence of liver fibrosis and steatosis. Methods: Untreated ...
Mucins in neoplastic spectrum of colorectal polyps: Can they provide predictions?
(2010)
Background: The significance of expression of different mucins in succession of malignant transformation of colorectal polyps is not determined yet. The aim of the present study was to determine the pattern of expression ...
Profile and frequency of p53 Gene alterations in gastritis lesions from Iran
(2010)
Background: It has been frequently shown that p53 alterations have an important role in the development of gastric cancers but there is no data on p53 alteration in gastric cancer and its precancerous lesions from Iran ...
MTHFR rs1801133 polymorphism and susceptibility to colorectal cancer in Iranian population: Evidence of a case-control study and meta-analysis
(2016)
Several studies have investigated whether MTHFR rs1801133 polymorphism contributes to risk of colorectal cancer (CRC), however the results are inconclusive. Aim: The purpose of this study was to investigate this hypothesis ...
Molecular epidemiology of Hepatitis Delta Virus (HDV) in Iran: A preliminary report
(2008)
To identify hepatitis delta virus (HDV) genetic variability and its circulating genotypes amongst infected Iranian patients, 25 patients with positive anti-HDV status from different parts of Iran were enrolled in this ...
C77G mutation in protein tyrosine phosphatase CD45 gene and autoimmune hepatitis
(2005)
Autoimmune hepatitis (AIH) is a rare frequent, multiplex disorder with undefined etiology. Susceptibility to autoimmune hepatitis results from complex interactions between genetic and environmental factors. In this study, ...
Prevalence of multiple drug-resistant helicobacter pylori strains among patients with different gastric disorders in Iran
(2015)
Emergence of multidrug-resistant (MDR) strains of Helicobacter pylori is a global health concern. This study was aimed to determine the frequency of MDR H. pylori strains in Iran. H. pylori isolates were obtained from ...
Seroprevalence of anti-helicobacter pylori antibodies in hepatitis B and C patients with cirrhosis: A case-control study
(2007)
Background: Cirrhosis is terminal stage of many chronic liver diseases like hepatitis C and hepatitis B. In some studies the role of helicobacter pylori has been demonstrated in progress of cirrhosis and its complications, ...
Evaluation of global genome methylation in gastritis lesion and its correlation with clinicopatological findings
(2009)
Global genome hypomethylation as an epigenetic phenomenon may induce (pre)neoplastic transformation through inducing chromosomal and genomic instability and activating oncogenes. Global genome hypomethylation has a fundamental ...