Now showing items 1-10 of 22
Glutathione-S-transferase M1, T1 and P1 gene polymorphisms in type I autoimmune hepatitis: A case-control study 
[No abstract available]
Gastro-oesophageal reflux disease and irritable bowel syndrome: A significant association in an Iranian population
Background: Gastro-oesophageal reflux disease and irritable bowel syndrome are common diseases, which may be related. Aim: To assess the association between gastro-oesophageal reflux disease and irritable bowel syndrome ...
Four novel germline mutations in the MLH1 and PMS2 mismatch repair genes in patients with hereditary nonpolyposis colorectal cancer
Background: Hereditary nonpolyposis colorectal cancer (HNPCC) is the most common cause of early onset hereditary colorectal cancer. In the majority of HNPCC families, microsatellite instability (MSI) and germline mutation ...
Sporadic colorectal polyps and mismatch repair proteins
Background: Colorectal cancers often arise from benign polyps. Adenomatous polyps and serrated polyps progress step by step to adenocarcinoma and change into malignant cancers. Genetic and epigenetic changes have correlation ...
High prevalence of reflux oesophagitis among upper endoscopies of Iranian patients
BACKGROUND AND AIM: To reinvestigate the prevalence of reflux esophagitis among upper endoscopies in a series of Iranian patients, considering the high prevalence of reflux esophagitis (76%) reported by an earlier Iranian ...
Symptom patterns and relative distribution of functional bowel disorders in 1,023 gastroenterology patients in Iran
Background and aims: There are scanty data on functional bowel disorder (FBD) patterns in Iran. This first-time study tried to provide preliminary data on relative distribution of different types of FBD and their symptom ...
T1764G1766 core promoter double mutants are restricted to Hepatitis B virus strains with an A1757 and are common in genotype D
To investigate the role of pre-core and basal core promoter (BCP) mutants in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (e-CHB) in Iran, Hepatitis B virus strains from 30 patients and 42 anti-HBe-positive ...
Association between MTHFR polymorphism (C677T) with nonfamilial colorectal cancer
The enzyme 5,10-methylene-tetrahydrofolate reductase (MTHFR) is linked to DNA methylation, synthesis, and repair. C677T is one of the most important polymorphisms in the MTHFR gene. The single nucleotide polymorphism C677T ...
Prevalence of multiple drug-resistant helicobacter pylori strains among patients with different gastric disorders in Iran
Emergence of multidrug-resistant (MDR) strains of Helicobacter pylori is a global health concern. This study was aimed to determine the frequency of MDR H. pylori strains in Iran. H. pylori isolates were obtained from ...
NOD2 exonic variations in Iranian Crohn's disease patients
Purpose The NOD2 gene is known to have a strong association with Crohn's disease, but different trends were reported in occurrence of NOD2 variants in distinct ethnicities. The aim of this study was to assess all exonic ...