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Preparation of chitosan-plasmid DNA nanoparticles encoding interleukin-12 and their expression in CT-26 colon carcinoma cells.

Hallaj-Nezhadi, S; Valizadeh, H; Dastmalchi, S; Baradaran, B; Jalali, MB; Dobakhti, F; Lotfipour, F (2011)

Interleukin-12 (Il-12) as a cytokine has been proved to possess antitumor effects via stimulating the immune system. Non-viral gene delivery systems exhibit low toxicity and are easier to prepare compared to their viral ...