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Profile and frequency of p53 Gene alterations in gastritis lesions from Iran
(2010)
Background: It has been frequently shown that p53 alterations have an important role in the development of gastric cancers but there is no data on p53 alteration in gastric cancer and its precancerous lesions from Iran ...
MTHFR rs1801133 polymorphism and susceptibility to colorectal cancer in Iranian population: Evidence of a case-control study and meta-analysis
(2016)
Several studies have investigated whether MTHFR rs1801133 polymorphism contributes to risk of colorectal cancer (CRC), however the results are inconclusive. Aim: The purpose of this study was to investigate this hypothesis ...
Gastro-oesophageal reflux disease and irritable bowel syndrome: A significant association in an Iranian population
(2008)
Background: Gastro-oesophageal reflux disease and irritable bowel syndrome are common diseases, which may be related. Aim: To assess the association between gastro-oesophageal reflux disease and irritable bowel syndrome ...
Four novel germline mutations in the MLH1 and PMS2 mismatch repair genes in patients with hereditary nonpolyposis colorectal cancer
(2009)
Background: Hereditary nonpolyposis colorectal cancer (HNPCC) is the most common cause of early onset hereditary colorectal cancer. In the majority of HNPCC families, microsatellite instability (MSI) and germline mutation ...
High prevalence of reflux oesophagitis among upper endoscopies of Iranian patients
(2007)
BACKGROUND AND AIM: To reinvestigate the prevalence of reflux esophagitis among upper endoscopies in a series of Iranian patients, considering the high prevalence of reflux esophagitis (76%) reported by an earlier Iranian ...
Appendectomy, tonsillectomy, and risk of inflammatory bowel disease: A case control study in Iran
(2006)
There is some controversy about the prevalence of appendectomy and tonsillectomy among patients with Crohn's disease and a lower rate of appendectomy among patients with ulcerative colitis (UC). The objective of this study ...
Symptom patterns and relative distribution of functional bowel disorders in 1,023 gastroenterology patients in Iran
(2006)
Background and aims: There are scanty data on functional bowel disorder (FBD) patterns in Iran. This first-time study tried to provide preliminary data on relative distribution of different types of FBD and their symptom ...
T1764G1766 core promoter double mutants are restricted to Hepatitis B virus strains with an A1757 and are common in genotype D
(2005)
To investigate the role of pre-core and basal core promoter (BCP) mutants in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (e-CHB) in Iran, Hepatitis B virus strains from 30 patients and 42 anti-HBe-positive ...
Association between insulin receptor gene exon 17 rs1799817 variant and risk of nonalcoholic fatty liver disease
(2017)
Background and objectives Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease characterized by accumulation of triglycerides in hepatocytes without alcohol consumption. Considering the key ...
Evaluation of the left-to-right shift of colon tumors in Iran: Is the trend changing?
(2015)
Background: Colorectal cancer (CRC) is the second cause of cancer-related deaths worldwide. There have been several studies reporting the proximal tumor shift, especially in Western countries. In the present study, we ...