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Molecular epidemiology of Hepatitis Delta Virus (HDV) in Iran: A preliminary report
To identify hepatitis delta virus (HDV) genetic variability and its circulating genotypes amongst infected Iranian patients, 25 patients with positive anti-HDV status from different parts of Iran were enrolled in this ...
Association of vitamin D receptor gene polymorphisms in Iranian patients with inflammatory bowel disease
Background and Aims: The vitamin D receptor (VDR) gene maps to a region on chromosome 12 shown to be linked to inflammatory bowel disease (IBD). Many studies have recognized the relation of VDR gene polymorphisms with ...
Frequency of three common mutations of CARD15/NOD2 gene in Iranian IBD patients
Background: The CARD15/NOD2 gene, located on the pericentromeric region of chromosome 16 (IBD 1) has been reported to have an association with IBD, especially Crohn's disease. Three common mutations of CARD15 are variably ...
Association between insulin receptor gene exon 17 rs1799817 variant and risk of nonalcoholic fatty liver disease
Background and objectives Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease characterized by accumulation of triglycerides in hepatocytes without alcohol consumption. Considering the key ...
NOD2 exonic variations in Iranian Crohn's disease patients
Purpose The NOD2 gene is known to have a strong association with Crohn's disease, but different trends were reported in occurrence of NOD2 variants in distinct ethnicities. The aim of this study was to assess all exonic ...