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The role of endothelial nitric oxide synthase -786 T/C polymorphism in cardiac instability following aneurysmal subarachnoid hemorrhage

Hendrix, P; Foreman, PM; Harrigan, MR; Fisher, WS; Vyas, NA; Lipsky, RH; Lin, M; Walters, BC; Tubbs, RS; Shoja, MM; Pittet, J-F; Mathru, M; Griessenauer, CJ (2017)

INTRODUCTION: Cardiac abnormalities are observed frequently after aneurysmal subarachnoid hemorrhage (aSAH). A subset of aSAH patients develops neurogenic cardiomyopathy, likely induced by catecholamine excess. Genetic ...

Association of cystathionine beta-synthase polymorphisms and aneurysmal subarachnoid hemorrhage

Hendrix, P; Foreman, PM; Harrigan, MR; Fisher, WS; Vyas, NA; Lipsky, RH; Lin, M; Walters, BC; Tubbs, RS; Shoja, MM; Pittet, J-F; Mathru, M; Griessenauer, CJ (2018)

OBJECTIVE Cystathionine b-synthase (CBS) is involved in homocysteine and hydrogen sulfide (H2S) metabolism. Both products have been implicated in the pathophysiology of cerebrovascular diseases. The impact of CBS polymorphisms ...